Research Article
Molecular Testing for Fragile X: Analysis of 5062 Tests from 1105 Fragile X Families—Performed in 12 Clinical Laboratories in Spain
Table 7
Paternal transmissions to their daughters.
| Paternal repeat size | Number with the same number of repeats | Number with regression | Median of the repeats average difference | % regression | Number with expansion | Median of the repeats average expansion | % expansion |
| 50–59 | 11 | 1 | 5.0 | 3.4 | 17 | 11.6 | 58.6 | 60–69 | 8 | 6 | 2.3 | 14.3 | 28 | 13.1 | 66.7 | 70–79 | 3 | 4 | 7.8 | 15.4 | 19 | 17.4 | 73.1 | 80–89 | 12 | 3 | 7.0 | 9.1 | 18 | 32.1 | 54.5 | 90–99 | 5 | 6 | 22.0 | 33.3 | 7 | 32.4 | 38.9 | 100–109 | 0 | 3 | 19.3 | 37.5 | 5 | 35.8 | 62.5 | 110–119 | 1 | 3 | 15.3 | 37.5 | 4 | 26.8 | 50.0 | 120–129 | 1 | 3 | 39.0 | 60.0 | 1 | 17.0 | 20.0 | 130–139 | 1 | 0 | 0 | 0.0 | 0 | 0 | 0.0 | 140–149 | 0 | 3 | 26.7 | 100.0 | 0 | 0 | 0.0 |
150-159
| 0 | 0 | 0 | 0.0 | 0 | 0 | 0.0 | 160–169 | 0 | 0 | 0 | 0.0 | 0 | 0 | 0.0 | 170–179 | 0 | 0 | 0 | 0.0 | 0 | 0 | 0.0 | 180–198 | 0 | 4 | 73.5 | 100.0 | 0 | 0 | 0.0 | 190–199 | 0 | 0 | 0 | 0.0 | 0 | 0 | 0.0 | >200 | 0 | 4a | 471.0 | 100.0 | 0 | 0 | 00.0 |
| Total | 42 | 40 | | 22.1 | 99 | | 54.7 |
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aThese 4 daughters had PMs, with their fathers being 2 high functioning males.
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