Molecular Testing for Fragile X: Analysis of 5062 Tests from 1105 Fragile X Families—Performed in 12 Clinical Laboratories in Spain

Table 7

Paternal transmissions to their daughters.

Paternal repeat size	Number with the same number of repeats	Number with regression	Median of the; repeats average difference	% regression	Number with expansion	Median of the; repeats average expansion	% expansion
50–59	11	1	5.0	3.4	17	11.6	58.6
60–69	8	6	2.3	14.3	28	13.1	66.7
70–79	3	4	7.8	15.4	19	17.4	73.1
80–89	12	3	7.0	9.1	18	32.1	54.5
90–99	5	6	22.0	33.3	7	32.4	38.9
100–109	0	3	19.3	37.5	5	35.8	62.5
110–119	1	3	15.3	37.5	4	26.8	50.0
120–129	1	3	39.0	60.0	1	17.0	20.0
130–139	1	0	0	0.0	0	0	0.0
140–149	0	3	26.7	100.0	0	0	0.0
150-159	0	0	0	0.0	0	0	0.0
160–169	0	0	0	0.0	0	0	0.0
170–179	0	0	0	0.0	0	0	0.0
180–198	0	4	73.5	100.0	0	0	0.0
190–199	0	0	0	0.0	0	0	0.0
>200	0	4^a	471.0	100.0	0	0	00.0
Total	42	40		22.1	99		54.7

 ^aThese 4 daughters had PMs, with their fathers being 2 high functioning males.