Research Article
Syn-Lethality: An Integrative Knowledge Base of Synthetic Lethality towards Discovery of Selective Anticancer Therapies
Table 3
Total statistics for human cancer Syn-Lethality database.
| Content | Number | Comments |
| SL pairs for human cancer from the literatures | 113 | NCBI PubMed abstracts | SL pairs for human cancer inferred from yeast | 1114 | Prediction according the orthologous | Screening methods | 3 | siRNA, shRNA, anticancer compound screening | Type of gene alteration | 5 | Mutation, deficient, inactivation, activation, overexpression | Annotated human genes | 647 | Only one gene of SL pairs related to human cancer also counted | Annotated signalling pathways of human genes | 647 | KEGG pathways |
|
|