Crude Extracts from Lycium barbarum Suppress SREBP-1c Expression and Prevent Diet-Induced Fatty Liver through AMPK Activation

Table 2

Effect of LBP on serum lipid profile of HFD-fed mice.

Variables	LFD	HFD	100 LBP + HFD
Blood glucose (mmol/L)	3.82±0.15	9.66±0.19	5.02±0.26^##
Total cholesterol (mmol/L)	1.24±0.56	2.09±1.14	1.38±2.04^#
HDL-cholesterol (mmol/L)	0.41±0.03	0.28±0.03	0.58±0.09^#
LDL-cholesterol (mmol/L)	0.13±0.12	0.55±0.25	0.28±0.46^#
AST (U/L)	78.4±8.70	244.6±12.45	141.7±5.26^##
ALT (U/L)	68.6±3.83	129.3±6.36	78.2±5.18^##
NEFA (umol/L)	244±10.8	480±26.5	261±33.6^###

Data are expressed as means ± SEM (𝑛=10 per group), ^#𝑃<0.05, ^##𝑃<0.01, and ^###𝑃<0.001, compared to HFD group. HDL: high-density lipoprotein; LDL: low-density lipoprotein; AST: aspartate aminotransferase; ALT: alanine aminotransferase; NEFA: nonesterified fatty acids.