In Vitro Inhibition of Hepatitis C Virus by Antisense Oligonucleotides in PBMC Compared to Hepatoma Cells

Figure 2

Multiple sequence alignment of loop IIId using ClustalW program. After sequencing, nine sequences comprising loop IIId were aligned using ClustalW program. Figure represents lower conservation with mutations C3-T3 in sample 4, A9-C9 for sample 3, G12-C12 for samples 6 and 9, G17-T17 for samples 5, 6, and 9, T18-C18 for samples 5, 6, and 9, and G19 insertion for samples 1, 5, 6, and 9.