Reliable Assessment and Quantification of the Fluorescence-Labeled Antisense Oligonucleotides In Vivo
Figure 2
Gel retardation assays to evaluate (a) the stable polyplexes formation and (b) the binding strength of polyplexes in acidic pH. Line1: pGa4D47, line2: pGu4D40, line 3: pDMAEMA, and line 4: ODNs. (c) Size and (d) zeta potential of polyplexes (■) pGa4D47, (●) pGu4D40, and (▲) pDMAEMA.