Bioassay Directed Isolation and Biological Evaluation of Compounds Isolated from Rubus fairholmianus Gard.

Figure 5

Close view of COX-2 docked with (a) diclofenac, (b) indomethacin, (c) 2-[(3-methylbutoxy) carbonyl] benzoic acid, and (d) 1-(2-hydroxyphenyl)-4-methylpentan-1-one. Isolated compounds (green color ball stick mode) docked with target protein COX-2 (stick mode) through hydrogen bond interaction (pink color dot).