Review Article

Thymic Epithelial Cell Development and Its Dysfunction in Human Diseases

Table 3

Foxn1 regulates multiple TEC development stages.

CapabilityRegulation aspectsReferences

DispensableTEPCs appearance[75ā€“77]
TEC fate-choice[77]
Medullary sublineage divergence[77]

IndispensableTEPCs into cTEC and mTEC sub-lineage[77]
TECs differentiation[76ā€“82]
TECs proliferation[83, 84]
TECs termination[77, 85, 86]
Thymic vascularization [87]