Review Article
Thymic Epithelial Cell Development and Its Dysfunction in Human Diseases
Table 3
Foxn1 regulates multiple TEC development stages.
| Capability | Regulation aspects | References |
| Dispensable | TEPCs appearance | [75ā77] | TEC fate-choice | [77] | Medullary sublineage divergence | [77] |
| Indispensable | TEPCs into cTEC and mTEC sub-lineage | [77] | TECs differentiation | [76ā82] | TECs proliferation | [83, 84] | TECs termination | [77, 85, 86] | Thymic vascularization | [87] |
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