Research Article

Strain-Dependent Induction of Human Enterocyte Apoptosis by Blastocystis Disrupts Epithelial Barrier and ZO-1 Organization in a Caspase 3- and 9-Dependent Manner

Figure 1

Time-dependent effect of Blastocystis ST-7 and ST-4 on the transepithelial resistance (TER) of Caco-2 cell monolayers. Confluent monolayers of Caco-2 cells were coincubated with ST-7 and ST-4 for the indicated times. TER was then measured as described in Section 2. ST-7 treated monolayers, compared to ST-4 and negative control, showed a significant drop in TER after 3, 6, 12, and 24 h ( value < 0.01). Values are means ± standard error (error bars) ( ).
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