Research Article

Strain-Dependent Induction of Human Enterocyte Apoptosis by Blastocystis Disrupts Epithelial Barrier and ZO-1 Organization in a Caspase 3- and 9-Dependent Manner

Figure 2

Dose-dependent effect of Blastocystis ST-4 and ST-7 on transepithelial resistant (TER) of Caco-2 cell monolayers. Confluent monolayers were coincubated with varying doses of ST-4 and ST-7 for 24 h. Compared to negative control, Blastocystis ST-7 induced a significant drop in Caco-2 TER at 0.25, 0.5, 1, and 2 × 108 parasite/mL ( value < 0.01). Values are mean ± standard error (error bars) ( ).
209163.fig.002