Effects of Parity and Serum Prolactin Levels on the Incidence and Regression of DMBA-Induced Tumors in OFA hr/hr Rats

Figure 6

β-Casein content and expression of mRNA for hormones receptors in mammary glands from primiparous rats (PL). Mammary β-casein content was lower (𝑃<0.01) in mammary glands from PL rats that had tumor regression (PLRegT) than in those that did not have tumors (PLNT) or did have no regressing tumors (PLT). (b) and (c) PRLR and ERα expressions were lower (𝑃<0.05 and 𝑃<0.01, resp.) in mammary glands from tumor-free PL rats compared to the other two groups.

(a)

(b)

(c)