Prediction on the Inhibition Ratio of Pyrrolidine Derivatives on Matrix Metalloproteinase Based on Gene Expression Programming

Table 3

Descriptors and their physical-chemical meanings, coefficient, error, and Student’s 𝑡-test in HM.

Number	Descriptor	Physical-chemical meanings	Coefficient	Error	𝑡-test
0		Intercept	−1.9501𝑒+02; 2.4570𝑒+00	1.2612𝑒+02	−1.5463
1	LUMO	LUMO energy		5.0431𝑒−01	4.8720
2	MRECO	Min resonance energy for a C–O bond	−3.6715𝑒+00	6.7200𝑒−01	−5.4635
3	KSIND	Kier shape index (order 3)	−2.0681𝑒−01	7.7119𝑒−02	−2.6816
4	ZX	ZX Shadow/ZX Rectangle	−7.0757𝑒+00	2.1621𝑒+00	−3.2726
5	MASEOAT	Min atomic state energy for a O atom	8.4808𝑒−01	4.3585𝑒−01	1.9458