Research Article

Enhanced Neural Cell Adhesion and Neurite Outgrowth on Graphene-Based Biomimetic Substrates

Figure 5

Neural cell adhesion (a) and neurite outgrowth (b) on graphene-based biomimetic substrates. Bright-field images of a glass coverslip with FBS-covered graphene on it (A1, scale bar = 10  m) and PC-12 cells on the boundary area between glass (lower) and graphene (upper) 3 days after cell culture (A2). SEM images (B1 and B2) of graphene patterned on a SiO2/Si substrate (B2, enlarged image of B1) and AFM image of neurite outgrowth from PC-12 cells on patterned graphene covered with FBS after 7 days of incubation (B3, scale bar = 20  m).
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