A Network Meta-Analysis on Randomized Trials Focusing on the Preventive Effect of Statins on Contrast-Induced Nephropathy

Table 5

Effect estimates for the risk of contrast-induced nephropathy excluding the study by Han et al. [4]. Results are reported as probability of being best treatment (Pbest) and odds ratios (OR) with 95% credible intervals of a given row item versus a corresponding column item. Thus, OR < 1 indicates lower risk in the corresponding row item and OR > 1 indicates lower risk in the corresponding column item.

Treatment	Atorvastatin high dose	Atorvastatin low dose	Rosuvastatin high dose	Simvastatin high dose	Simvastatin low dose	Placebo or no statin
Atorvastatin high dose	Pbest = 20%	OR = 0.32 (0.15–0.65)	OR = 1.22 (0.66–2.33)	OR = 0.65 (0.15–3.85)	OR = 0.19 (0.03–1.37)	OR = 0.47 (0.31–0.70)
Atorvastatin low dose	OR = 3.12 (1.53–6.73)	Pbest < 0.1%	OR = 3.85 (1.47–11.09)	OR = 2.08 (0.36–14.08)	OR = 0.60 (0.08–4.98)	OR = 1.45 (0.62–3.45)
Rosuvastatin high dose	OR = 0.82 (0.43–1.51)	OR = 0.26 (0.10–0.68)	Pbest = 34%	OR = 0.53 (0.12–3.23)	OR = 0.16 (0.02–1.22)	OR = 0.38 (0.22–0.65)
Simvastatin high dose	OR = 1.54 (0.26–6.87)	OR = 0.48 (0.07–2.77)	OR = 1.90 (0.31–8.56)	Pbest = 20%	OR = 0.29 (0.10–0.78)	OR = 0.72 (0.13–3.06)
Simvastatin low dose	OR = 5.24 (0.73–32.12)	OR = 1.67 (0.20–12.66)	OR = 6.46 (0.82–41.28)	OR = 3.42 (1.28–10.03)	Pbest = 0.2%	OR = 2.46 (0.35–14.17)
Placebo or; no statin	OR = 2.15 (1.42–3.28)	OR = 0.69 (0.29–1.61)	OR = 2.63 (1.54–4.55)	OR = 1.39 (0.33–7.69)	OR = 0.41 (0.07–2.86)	Pbest = 0