Research Article

ECM Inspired Coating of Embroidered 3D Scaffolds Enhances Calvaria Bone Regeneration

Figure 2

Schematic presentation of ultrasonographic examination of the rabbit skull and image analysis. (a) Defect location and ultrasound probe positioning during examination. (b) Schematic drawing (left) and corresponding ultrasound image (right) of an empty defect 24 h after surgery. (c) Schematic drawing (left) and ultrasound image (right) of a PCL coll I/cs coated scaffold at 12 weeks after surgery with evident new tissue formation. A defined ROI (red square) was used to quantify the tissue formation within the defect area and both parietal bone ends are marked in green.
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(c)