Independent Value of Cardiac Troponin T and Left Ventricular Global Longitudinal Strain in Predicting All-Cause Mortality among Stable Hemodialysis Patients with Preserved Left Ventricular Ejection Fraction

Table 1

Baseline clinical characteristics of stable hemodialysis patients with preserved left ventricular ejection fraction.

	cTnT Tertiles			𝑃 for trend
	Lower (cTnT ≤ 0.02 ng/mL, 𝑛=30)	Middle (0.02 < cTnT ≤ 0.042 ng/mL, 𝑛=29)	Upper (cTnT > 0.042 ng/mL, 𝑛=29)
Age (years)	64.0±13.0	67.9±8.7	68.4±11.6	0.27
Male, 𝑛 (%)	11 (37%)	9 (31%)	12 (42%)	0.71
BMI (kg/m^2)	21.3±3.0	22.6±2.5	21.2±2.9	0.15
Kt/v	1.75±0.22	1.71±0.24	1.66±0.22	0.30
IDWG, (kg)	2.63±0.83	2.92±1.02	2.78±1.25	0.60
IDWG, (%)	5.1±1.8	5.2±1.6	5.1±2.3	0.98
Hemodialysis duration (years)	6.5 (4, 9)	4.4 (2, 9.9)	4 (1.8, 6.4)	0.31
SBP (mmHg)	143.0±13.2	152.2±16.3	144.1±15.2	0.93
DBP (mmHg)	73.9±8.7	81.0±7.8	76.2±10.2	0.44
Heart rate	74.7±11.4	75.8±12.4	75.5±12.6	0.94
Prevalent CAD	8 (27%)	11 (38%)	12 (41%)	0.46
Diabetes mellitus	7 (23%)	16 (55%)	22 (76%)	<0.001*
Hypertension	27 (90%)	25 (86%)	25 (86%)	0.85
LV hypertrophy^#	28 (93%)	27 (93%)	27 (93%)	0.95
ACEI/ARB	17 (57%)	18 (62%)	13 (45%)	0.40
𝛽-Blocker	15 (50%)	11 (38%)	15 (52%)	0.40
CCB	15 (50%)	17 (59%)	18 (62%)	0.48
Statin	6 (20%)	4 (14%)	5 (17%)	0.94
Calcium (mg/dL)	9.4±0.9	9.1±0.7	9.2±0.7	0.26
Phosphate (mg/dL)	4.4±1.3	4.8±1.3	4.1±1.1	0.19
Albumin (g/dL)	3.3±0.5	3.4±0.3	3.2±0.4	0.21
Cholesterol (mg/dL)	163.1±35.7	168.6±41.5	157.6±35.7	0.55
hsCRP (mg/dL)	0.26 (0.14, 0.63)	0.66 (0.18, 0.99)	0.45 (0.19, 1.95)	0.12
IL-6 (pg/mL)	9.5 (7.3, 16.3)	9.7 (6.9, 13.7)	10.6 (6.3, 19.1)	0.85
PICP (ng/mL)	843.6±398.5	802.1±331.8	952.8±444.9	0.34

Continuous data are expressed as the mean ± standard deviation or the median (25th and 75th percentiles); categorical data are expressed as the number (percentage). A nonparametric Kruskal-Wallis test was used for nonnormally distributed data.
^∗𝑃<0.05; ^#LV hypertrophy was diagnosed by echocardiography.
Abbreviations: ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin II-receptor blocker; BMI: body mass index; CAD: coronary artery disease; CCB: calcium channel blocker; cTnT: cardiac troponin T; DBP: diastolic blood pressure; hsCRP: high-sensitivity C-reactive protein; IDWG: interdialytic weight gain; IL: interleukin; Kt/V: an indicator of dialysis adequacy (𝐾: urea clearance; 𝑡: dialysis time; 𝑉: urea distribution volume); LV: left ventricle; PICP: procollagen type I C-terminal peptide; SBP: systolic blood pressure.