Activity Exerted by a Testosterone Derivative on Myocardial Injury Using an Ischemia/Reperfusion Model
Figure 10
Effect exerted by indomethacin (INDOMET) and PINANE TXA2 (PINANE) in presence and absence of testosterone derivative (T-D) on cardiac ischemia/reperfusion.The results showed that T-D significantly reduced infarct size expressed as a percentage of the area at risk compared with testosterone and the vehicle-treated hearts (). However, this effect was partially blocked by INDOMET and PINANE. Other data indicate that INDOMET significantly decreased infarct size () in comparison with PINANE. Each bar represents the mean ± SE of 6 experiments.
