Research Article

Activity Exerted by a Testosterone Derivative on Myocardial Injury Using an Ischemia/Reperfusion Model

Figure 2

Synthesis of 4-(4-chloro-phenyl)-1-{4-(4-fluoro-phenyl)-4-[2-(17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenan thren-3-ylideneamino)-ethylimino]-butyl}-piperidin-4-ol (5). Reaction of 1-[4-(2-amino-ethylimino)-4-(4-fluoro-cyclohexyl)-butyl]-4-(chloro-phenyl)-piperidin-4-ol (3) with testosterone (2) to form the compound 3. (ii) = boric acid.
217865.fig.002