Early Monitoring Antiangiogenesis Treatment Response of Sunitinib in U87MG Tumor Xenograft by ¹⁸F-FLT MicroPET/CT Imaging

Figure 1

Antitumor activity of Sunitinib in U87MG xenografts. (a) Tumor volume or (V−V₀)/V₀ of U87MG tumor-bearing mice treated with vehicle or Sunitinib. There was significant difference for the tumor size between the Sunitinib group and control group after day 11 (𝑃=0.015). (b) Body weight of U87MG tumor-bearing mice treated with vehicle or Sunitinib. There was no difference for the mice weight between the Sunitinib group and control group. ^∗𝑃<0.05 and ^∗∗𝑃<0.01.

(a)

(b)