Circulating Conventional and Plasmacytoid Dendritic Cell Subsets Display Distinct Kinetics during In Vivo Repeated Allergen Skin Challenges in Atopic Subjects

Table 1

Subject characteristics and summary of results for peripheral and tissue DC subset recruitment.

	Subject 1		Subject 2		Subject 3		Subject 4		Subject 5		Subject 6		Subject 7		Subject 8		Subject 9		Subject 10		Subject 11		Subject 12
Gender	M		F		F		M		F		F		M		M		F		F		M		F
Age	30		53		23		30		31		28		40		31		31		27		26		28
IgE	830		1100		720		54		106		71		19		19		44		235		630		120
	Peripheral dendritic cells (% of total WBC)
cDCs baseline	0,3986		0,209		0,2445		0,1706		0,2122		0,2147		0,1283		0,2223		0,2102		0,1334		0,178		0,175
cDCs 1 h	0,3602		0,2454		0,2016		0,1544		0,1804		0,1845		0,1421		0,1887		0,1778		0,174		0,154		0,1444
cDCs 24 h	0,3731		0,1571		0,2424		0,1089		0,2424		0,1908		0,1296		0,1777		0,1132		0,1278		0,1057		0,1011
cDCs 5 w	0,2706		0,2307		0,2923		0,1262		0,174		0,2711		0,1527		0,1368		0,1593		0,1124		0,1162		0,1282
pDCs baseline	0,1284		0,1071		0,2468		0,1213		0,225		0,2554		0,1139		0,1798		0,0553		0,1413		0,2369		0,244
pDCs 1 h	0,1102		0,105		0,1895		0,0828		0,1708		0,1681		0,1175		0,1105		0,0581		0,0524		0,167		0,104
pDCs 24 h	0,0859		0,1313		0,2099		0,0732		0,144		0,1982		0,119		0,1503		0,0647		0,1526		0,212		0,2059
pDCs 5 w	0,0214		0,0013		0,2119		0,066		0,3738		0,1559		0,1715		0,078		0,1308		0,0907		0,2113		0,198
	Tissue dendritic cells (cells per mm^2)
	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL	ALL	DIL
cDCs 24 h	5	3	24	8	15	7	34	12	12	5	21	13	58	25	24	19	17	5	22	5	23	9	30	8
cDCs 5 w	14	6	16	8	20	13	10	13	23	10	30	8	25	15	15	48	29	17	25	5	27	6	14	6
pDCs 24 h	12	10	6	8	8	5	12	15	4	4	24	14	5	2	5	3	3	2	18	10	7	3	12	10
pDCs 5 w	10	8	12	5	4	25	8	6	9	6	11	5	14	10	10	16	6	3	4	1	5	4	5	8