Research Article
The Association of HLA-Class I and Class II with Hodgkin’s Lymphoma in Iranian Patients
Table 3
The susceptible and protective alleles or haplotypes in HD.
| | Susceptible and protective alleles or haplotypes | Study |
| | Susceptible allele: HLA-B18 | Amiel 1967, Svejgaard et al., 1975, Bjorkholm et al., 1975, [8, 24, 25] |
| Susceptible haplotype: DRB1*15:01-DQA1*01:02-DQB1*06:02
Protective haplotypes: DRB1*16:01-DQA1*01:02-DQB1*05:02, DRB1*04:04-DQA1*03:01-DQB1*03:02, DRB1*07:01-DQA1*02:01-DQB1*03:03 and DRB1*14:01-DQA1*01:01-DQB1*05:03 | Klitz et al., 1994, [11] |
| Susceptible allele: HLA-DRB1*15:01
Protective allele: HLA-DRB1*01:01 | Taylor et al., 1996, [26] |
| | Susceptible haplotype: DRB1*15:01-DQA1*01:02-DQB1*06:02 | Harty et al., 2002, [28] |
| | Susceptible alleles: HLA-DRB1*04:03 and HLA-DRB1*12:02 | Al-Tonbary et al., 2004 [27] |
| Susceptible allele: HLA-DRB1*15:01
Protective allele: HLA-DRB1*07:01 | Moutsianas et al., 2011, [23] |
| | Susceptible alleles: HLA-A*68, HLA-B*51 and HLA-DRB1*15 | Present study |
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