BioMed Research International / 2014 / Article / Tab 4

Research Article

CpG Island Methylator Phenotype and Prognosis of Colorectal Cancer in Northeast China

Table 4

Survival analysis on CRC patients according to CIMP status in tumor tissue in different tumor stages.

CIMP statusStages I-II ()Stages III-IV ()
UnivariateMultivariateUnivariateMultivariate
HR and 95% CIHR and 95% CIHR and 95% CIHR and 95% CI

CIMP-H versus CIMP-L/00.69 (0.17–2.91)0.620.52 (0.12–2.22)0.381.81 (1.02–3.24)0.041.75 (0.95–3.23)0.07
CIMP-H versus CIMP-L0.74 (0.17–3.14)0.680.57 (0.13–2.48)0.461.73 (0.96–3.11)0.071.50 (0.80–2.81)0.20
CIMP-L versus CIMP-00.66 (0.27–1.60)0.350.57 (0.23–1.41)0.221.42 (0.60–3.34)0.432.06 (0.77–5.53)0.15
CIMP-H versus CIMP-00.71 (0.32–1.58)0.400.56 (0.21–1.49)0.241.55 (0.96–2.49)0.071.67 (1.00–2.81)0.05

Multivariate analysis, adjusted for age at diagnosis, tumor stage, tumor differentiation, and tumor location.

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