Diagnosis System for Hepatocellular Carcinoma Based on Fractal Dimension of Morphometric Elements Integrated in an Artificial Neural Network

Figure 1

(a)–(c) An overview of the interface designed for selecting and calculating FDs. (a) An individual image is loaded; then values for the reference hues and standard deviations as well as the desired saturations can be either typed in the designated box or manually selected with the mouse cursor on the image representation on the left. (b) The operator receives a visual confirmation of the selection and can further adjust the parameters in order to make it more accurate. (c) The FD is calculated and a graphical representation of the log-log function is presented to the user. After the cycle is completed, the user can batch-process entire series of images. Values for FDs are automatically saved as lists of comma-separated values and are fed to the ANN system.