Research Article

Protective Effect of Ethanolic Extract of Tabernaemontana divaricata (L.) R. Br. against DEN and Fe NTA Induced Liver Necrosis in Wistar Albino Rats

Table 1

Changes in the level of uric acid, bilirubin, AST, ALT, and ALP in serum.

ParticularsGroup IGroup IIGroup IIIGroup IVGroup VGroup VIGroup VII

Uric acid (mg/dL)1.54 ± 0.01a3.24 ± 0.02b2.2 ± 0.01c1.56 ± 0.01a1.5 ± 0.03d1.39 ± 0.05e1.42 ± 0.08e
Bilirubin (mg/dL)0.9 ± 0.05a2.37 ± 0.06b1.31 ± 0.06c0.86 ± 0.07a0.9 ± 0.05a0.87 ± 0.03a0.85 ± 0.05a
AST (IU/L) 32.85 ± 1.59a101.13 ± 0.86b57.32 ± 1.51c34.39 ± 0.86d32.85 ± 1.12a32.68 ± 0.77a34.03 ± 0.92ad
ALT (IU/L) 68.99 ± 0.49a138.77 ± 2.97b90.59 ± 0.79c69.85 ± 0.24a72.89 ± 1.31d68.69 ± 0.71a73.24 ± 0.48d
ALP (IU/L) 72.94 ± 0.32a254.0 ± 0.45b141.56 ± 0.41c73.65 ± 0.38d72.62 ± 0.41a70.68 ± 0.64a74.1 ± 0.63d

Values are expressed as mean ± SD ( ).
Values not sharing the common superscript differ significantly (DMRT).