Research Article

Adhesion of Pancreatic Cancer Cells in a Liver-Microvasculature Mimicking Coculture Correlates with Their Propensity to Form Liver-Specific Metastasis In Vivo

Figure 5

Expression of TMNK-1 phenotypic marker VAP-1 (a) and LYVE-1 (b) in various culture conditions. (a1), (a2), (b1), and (b2) and (a3), (a4), (b3), and (b4) show representative images showing the expression of the respective markers in the collagen coated and gel cultures, respectively. Similarly, (a5) and (b5) and (a6) and (b6) show the average pixel intensity of the immunostaining in the cultures. Intensity was averaged from at least five images taken from two samples for each condition. Columns and error bars represent mean ± SEM. Statistical significance is shown using symbols , , and .
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(a)
241571.fig.005b
(b)