H-CRRETAWAC-OH, a Lead Structure for the Development of Radiotracer Targeting Integrin α₅β₁?

Table 2

Binding affinity () of the different compounds tested using the immobilized integrins and ¹²⁵I-echistatin as radioligand (in bold average and standard deviation of the mean are given).

Peptide	nM	M	M
H-C*RRETAWAC*-OH	10	>50 ()	n.d.
	3.9
	2.1
	5.3 ± 4.1
H-C*ARETAWAC*-OH	39.000	n.d.	n.d.
	40.000
	40.000 ± 1.000
H-C*RAETAWAC*-OH	17	n.d.	n.d.
	15
	16 ± 1
H-C*RRATAWAC*-OH	>50.000 ()	n.d.	n.d.
H-C*RREAAWAC*-OH	8.000	n.d.	n.d.
	11.000
	10.000 ± 2.000
H-C*RRETAAAC*-OH	>50.000 ()	n.d.	n.d.
FProp-C*RRETAWAC*-OH (1)	41	>50 ()	>50 ()
	47
	44 ± 3
FProp-C*RRETAWAC*-OH (2)	127	>50 ()	>50 ()
	26
	77 ± 50