BioMed Research International / 2014 / Article / Tab 3

Research Article

A Knowledge-Driven Approach to Extract Disease-Related Biomarkers from the Literature

Table 3

The top 10 disease-biomarker associations. Disease-biomarker associations were ranked according to ScoreDB (see Section 2 for more details). The complete list of the associations is available at http://ibi.imim.es/biomarkers/.

ScoreDisease name (CUIa)Gene symbol (Gene IDb) Number of abstracts

4076.42NEOPLASM (C0027651)TP53 (7157)3,042
3930.25NEOPLASM (C0027651)ERBB2 (2064)2,582
3441.32NEOPLASM (C0027651)CEACAM5 (1048)2,234
2733.92IMMUNODEFICIENCY DISORDER (C0021051)CD4 (920)1,548
2546.27NEOPLASM (C0027651)EGFR (1956)1,710
2028.21LEUKEMIA (C0023418)CD34 (947)1,071
1988.57NEOPLASM (C0027651)ESR1 (2099)1,179
1943.15NEOPLASM (C0027651)AFP (174)1,169
1915.15NEOPLASM (C0027651)CD34 (947)1,108
1836.03MALIGNANT NEOPLASTIC DISEASE (C0006826)KLK3 (354)936

Concept unique identifier at UMLS.
NCBI gene identifier.