Clinical Factors Associated with Response or Survival after Chemotherapy in Patients with Waldenström Macroglobulinemia in Korea

Table 3

Multivariate analysis for response and survival.

Value	ORR			OS
	RR	95% CI	𝑃 value	RR	95% CI	𝑃 value
Age, years
<65
≥65				1.021	0.350–2.980	0.970
ALC, ×10^9/L
<1.0
≥1.0	0.362	0.060–2.193	0.369
ECOG (%)
0-1
≥2	2.006	0.711–5.660	0.188	0.421	0.147–1.208	0.108
Serum albumin, g/dL
<3.5
≥3.5				1.123	0.264–4.772	0.875
ISS (%)
I
II				0.439	0.078–2.486	0.352
III				0.209	0.066–0.665	0.008
Treatment regimen
Novel agent combined chemotherapy
Conventional chemotherapy	5.048	1.032–24.702	0.046	0.368	0.075–1.803	0.217

ORR: overall response rates; OS: overall survival rates; RR: relative risk; 95% CI: 95% confidence interval; ALC: absolute lymphocyte count; ECOG: Eastern Cooperative Oncology Group performance status; ISS: international staging system.