Pu-Erh Tea Extract Induces the Degradation of FET Family Proteins Involved in the Pathogenesis of Amyotrophic Lateral Sclerosis

Figure 4

Effect of PTE on cell viability and FUS/TLS mRNA expression in SK-N-SH cells. Cells were treated with different concentrations of PTE for 24 h. (a) Cell viability was measured by trypan blue staining. Percentage viability was defined as the number of viable cells in treated versus untreated cells. (b) FUS/TLS mRNA expression was analyzed by quantitative RT-PCR. Values are mean ± SEM of three independent experiments. *𝑃<0.05, **𝑃<0.01, and ***𝑃<0.001 compared with untreated control.

(a)

(b)