Coexpression of SFRP1 and WIF1 as a Prognostic Predictor of Favorable Outcomes in Patients with Colorectal Carcinoma

Table 5

Kaplan-Meier and Cox multivariate proportional hazard analysis for clinicopathological characteristics of CRC patients.

Characteristics	Univariate analysis log-rank	𝑃	Multivariate analysis hazard ratio (95%)	𝑃
Age (year)
≤65	1.047	0.306
>65
Gender
Male	0.407	0.523
Female
Lesion sites
Right	2.627	0.105
Left
Architectural features
Mucus	3.227	0.072
Nonmucinous
Tumor diameter
≤4.5 cm	0.032	0.858
>4.5 cm
Invasion
T1-T2	5.579	0.018		NS
T3-T4
Lymph metastasis
N0	9.773	0.002		NS
N1-N2
Liver metastasis
Negative	5.583	0.018		NS
Positive
TNM stage^a
I-II	10.983	0.001	0.391 (0.201–0.760)	0.006
III-IV			1
WIF1 and SFRP1 expression
WIF(+)/SFRP1(+)	5.477	0.019	0.428 (0.187–0.983)	0.045
The others			1

aAccording to the 2002 version of the American Joint Committee on Cancer (AJCC) and the International Union Against Cancer (UICC).
NS: variables not significant in the equation, 𝑃>0.05.