Impact of Statins on Cognitive Deficits in Adult Male Rodents after Traumatic Brain Injury: A Systematic Review

Table 2

Criteria for study inclusion/exclusion.

Inclusion criteria	Exclusion criteria
(1) Statins were administered.	(1) Statins were not administered.
(2) Experimental TBI was induced in rodents.	(2) No control group was used.
(3) Cognitive function was measured by the MWM.	(3) Nonimpact (e.g., cortical ablation) or penetrating (e.g., missile-induced) TBI was performed.
(4) Male rodents (i.e., rats or mice) were used.	(4) Treatment group was administered another neuroprotective agent in addition to a statin.
(5) Article was published in English or Chinese language.	(5) Other types of animals (e.g., sheep, cats, and dogs) were used.
(6) A TBI treatment group was treated with a pharmacological agent, and a control group was administered a placebo after injury.	(6) Only biochemical or physiological outcomes of treatment efficacy were assessed.
	(7) Samples included female rodents.
	(8) Duplicate publications.