Construction of a Novel Liver-Targeting Fusion Interferon by Incorporation of a Plasmodium Region I-Plus Peptide

Figure 7

Fluorescence photomicrographs of tissue from an adult BALB/c mouse after being incubated with IFN-CSP solution. (a) Heart. (b) Liver. (c) Spleen. (d) Lung. (e) Kidney. 1: green fluorescent labeling of IFN-CSP stained by anti-IFN antibody. 2: blue nuclear stained with DAPI. 3: merged images of 1 and 2. Note the distinct green fluorescent labeling of IFN-CSP in liver, but not in heart, spleen, lung, or kidney. Bar, 100 μm, is the same for all photomicrographs. Arrows indicate two examples of sinusoidal capillary profiles.