Protective Role of 5-Lipoxigenase during Leishmania infantum Infection Is Associated with Th17 Subset

Figure 2

Lack of 5-LO interferes on neutrophil migration. The neutrophils were gated based on their characteristic size (FSC) and granularity (SSC) (a). The dot plots represent the frequency of neutrophils population characterized by (upper gate) and (lower gate) by flow cytometry (b). The bar graphs display the percentage and the absolute number characterized as population (c) or (d) in the spleen from the WT and mice at the 6th wpi or from uninfected mice (naïve mice). The data are expressed as the mean ± SEM, N = 5-6. compared with the WT naïve group, compared with the WT infected group, and compared with naïve group.