Research Article

Protective Role of 5-Lipoxigenase during Leishmania infantum Infection Is Associated with Th17 Subset

Figure 5

5-LO activity is required for dendritic cell activation into the inflammation site. The in vivo surface markers of DCs from the WT (white bars) or (black bars) infected mice at the 6th wpi were determined by flow cytometry. The dot plots represent the frequency of CD40 (a), CD86 (b), and MHC-II (c) in the population. All analyses were performed on CD11b+ gated cells. The data are expressed as the mean ± SEM, N = 5-6. compared to the WT group.
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