Evidence for Association of the E23K Variant of KCNJ11 Gene with Type 2 Diabetes in Tunisian Population: Population-Based Study and Meta-Analysis

Table 1

Clinical and biochemical characteristics of study subjects.

Characteristics	T2DM (𝑛=250)	Control (𝑛=267)	𝑃 value
Gender (men/women)	94/156	105/162	0.65*
Age (years)	60.2±10.5	53.7±11.6	<10^†−4
Duration of diabetes (years)	14.31±9.26	—	—
Age at diagnosis (years)	45.6±9.5	—	—
HbA1c (% (mmol/mol))	9.1±1.9 (76±20)	—	—
Height (cm)	161.9±9.7	162.24±9.6	0.71^†
Weight (kg)	75.4±13.7	74±13.6	0.3^†
Mean BMI (kg/m^2)	28.9±5.5	28.2±5.3	0.2^†
Systolic blood pressure (mmHg)	14.5±2	13.4±2.2	<10^†−4
Diastolic blood pressure (mmHg)	8.3±1.1	8.1±5.2	0.75^‡
Fasting plasma glucose (mmol/L)	11.5±4.1	5.2±0.5	<10^‡−4
Total cholesterol (mmol/L)	5.0±1.1	5.0±1	0.95^†
Triglycerides (mmol/L)	1.7±0.9	1.3±0.6	<10^‡−4
HDL-cholesterol (mmol/L)	1.2±0.4	1.5±0.4	<10^†−4
LDL-cholesterol (mmol/L)	2.8±0.9	3±0.9	0.27^†

Data are expressed as means ± SD (standard deviation). *Pearson’s chi-square test. ^†Student’s 𝑡-test for equal variances. ^‡Welch’s 𝑡-test for unequal variances.