Effects of Converting Tacrolimus Formulation from Twice-Daily to Once-Daily in Liver Transplantation Recipients
Figure 2
The serum levels of AST and ALT before and after formulation conversion. (a) The median (interquartile) level of AST was elevated from 24 (20 to32) U/L to 26 (21.0 to 34.5) U/L at 1 month (), reached its peak (26 (20 to 36) U/L) at 3 months (), and returned to 23 (19 to 31) U/L at 6 months () and 24 (20 to 32) U/L at 9 months (). (b) The median (interquartile) level of ALT was elevated from 20 (14 to 29) U/L to 21 (15 to 33) U/L at 1 month (), reached its peak (20 (15 to 36) U/L) at 3 months (), and returned to 18 (14 to 30) U/L at 6 months () and 20 (14 to 30) U/L at 9 months ().