Research Article

Genetic Polymorphisms of ORAI1 and Chronic Kidney Disease in Taiwanese Population

Table 2

Difference in the value of eGFR among CKD patients stratified by different ORAI1 genotypes.

SNPGenotypeSample number (%)eGFRa

rs12320939TT122 (21.2)31.75 ± 24.28
TG295 (51.2)32.26 ± 24.04
GG159 (27.6)31.34 ± 24.28
value0.9229
Adjusted valueb0.8764

CC50 (8.7)34.64 ± 23.93
rs12313273CT245 (42.5)31.08 ± 22.45
TT281 (48.8)31.90 ± 24.70
value0.6229
Adjusted valueb0.7209

TT98 (17.0)29.06 ± 20.71
rs7135617TG285 (49.6)32.71 ± 24.31
GG192 (33.4)32.29 ± 25.44
value0.4138
Adjusted valueb0.3691

CC71 (12.3)33.49 ± 25.23
rs6486795CT271 (47.0)31.79 ± 22.61
TT235 (40.7)31.93 ± 24.90
value0.8619
Adjusted valueb0.8608

CC56 (9.7)34.36 ± 26.12
rs712853CT238 (41.4)31.95 ± 24.39
TT281 (48.9)31.53 ± 23.09
value0.7220
Adjusted valueb0.7038

Means ± SD. bAdjusted age by linear regression.