Research Article

Transgenic Rat Model of Huntington’s Disease: A Histopathological Study and Correlations with Neurodegenerative Process in the Brain of HD Patients

Table 2

Results of Kruskal-Wallis Multiple-Comparison -Value Test (Dunn’s Test) of the groups of rats: “young_wt” and “young_tgHD” are groups of rats 3 and 6 months (0–6 months) old; “old_wt” and “old_tgHD” are groups of rats 12, 18, and 24 months old (>6 months). Asterisk indicates significantly different pairs of groups (Bonferroni test: medians are significantly different if -value is > 2.6383). Statistically significant is a difference in the median diameter of neuronal nuclei in “old_tgHD” group in comparison with all other evaluated groups.

Groupyoung_tgHDyoung_wtold_tgHDold_wt

young_tgHD
young_wt0.2844
old_tgHD4.9557*4.5959*
old_wt1.8131.46464.5135*