The Influence of BMX Gene Polymorphisms on Clinical Symptoms after Mild Traumatic Brain Injury
Table 3
(a) Difference in BAI score among mTBI patients stratified by different BMX genotypes (First week). (b) Difference in BAI score among mTBI patients stratified by different BMX genotypes (sixth week).
(a)
SNP
Genotype
Number
Grade 1 (0–9)
Grade 2 (10–18)
Grade 3 (19–29)
Grade 4 (30–63)
aOR (95% CI) P value
bFisher’s exact test P value
rs35697037
AA + AG
107
67 (62.6)
22 (20.6)
14 (13.1)
4 (3.7)
1.40
GG
79
50 (63.3)
19 (24.0)
7 (8.9)
3 (3.8)
(0.61–3.21)
0.5352
—
rs16979956
TT + CT
3
1 (33.3)
0 (0.0)
1 (33.3)
1 (33.3)
12.08
CC
183
116 (63.4)
41 (22.4)
20 (10.9)
6 (3.3)
(1.06–138.01)
0.0597
rs1877752
TT + CT
9
4 (44.4)
2 (22.2)
3 (33.3)
0 (0.0)
3.04
CC
177
113 (63.8)
39 (22.0)
18 (10.2)
7(4.0)
(0.71–12.95)
0.1159
0.1372
rs16997078
GG + AG
7
4 (57.1)
1 (14.3)
0 (0.0)
2 (28.6)
2.35
AA
179
113 (63.1)
40 (22.4)
21 (11.7)
5 (2.8)
(0.43–12.78)
0.3080
0.2841
is labeled in bold. Grade 1 + Grade 2 versus Grade 3 + Grade 4. b20% of cells has expected count less than 5, Fisher’s exact test would be performed.
(b)
SNP
Genotype
Number
Grade 1 (0–9)
Grade 2 (10–18)
Grade 3 (19–29)
Grade 4 (30–63)
aOR (95% CI) P value
bFisher’s exact test P value
rs35697037
AA + AG
64
46 (71.9)
10 (15.6)
7 (10.9)
1 (1.6)
1.29
GG
40
32 (80.0)
4 (10.0)
3 (7.5)
1 (2.5)
(0.36–4.58)
0.6978
0.7635
rs16979956
TT + CT
1
1 (100.0)
0 (0.0)
0 (0.0)
0 (0.0)
0
CC
103
77 (74.8)
14 (13.6)
10 (9.7)
2 (1.9)
—
0.7167
1.0000
rs1877752
TT + CT
4
3 (75.0)
1 (25.0)
0 (0.0)
0 (0.0)
0
CC
100
75 (75.0)
13 (13.0)
10 (10.0)
2 (2.0)
—
0.4614
1.0000
rs16997078
GG + AG
4
2 (50.0)
1 (25.0)
1 (25.0)
0 (0.0)
2.70
AA
100
76 (76.0)
13 (13.0)
9 (9.0)
2 (2.0)
(0.26–28.23)
0.3901
0.3923
Grade 1 + Grade 2 versus Grade 3 + Grade 4. b20% of cells has expected count less than 5, Fisher’s exact test would be performed.
