Caspase Mediated Synergistic Effect of Boswellia serrata Extract in Combination with Doxorubicin against Human Hepatocellular Carcinoma
Figure 7
Showing liver section prepared from tissues of different treatment groups and stained by H&E staining. (a) Control group showing normal polygonal cells with prominent round nuclei and well preserved cytoplasm and visible central vein; (b) DOX intoxicated group showing massive fatty changes, necrosis, ballooning degeneration and broad infiltration of lymphocytes, loose cellular boundaries, vacuolated hepatocytes, and mild periportal inflammatory cell infiltration; (c) group treated with B. serrata extract at 250 mg/kg showing more or less normal lobular pattern with mild degree of fatty changes; (d) group treated with B. serrata extract at 500 mg/kg showing centrizonal area with almost nil inflammatory cell infiltration; and (e) standard group showing almost normal hepatic architecture.
