Added Value of QuantiFERON TB-Gold in-Tube for Detecting Latent Tuberculosis Infection among Persons Living with HIV/AIDS
Table 4
QFT-GIT results according to characteristics of 300 patients with AIDS in Brasilia, Federal District, Brazil.
Characteristics
QTF-GIT positive (%)
QTF-GIT negative (%)
Nonadjusted OR (95% CI)
Adjusted OR (95% CI)
Sex
Male
12 (5.6)
202 (94.4)
2.46 (0.54–11.26)
4.70 (0.86–25.59)
Female
2 (2.4)
83 (97.6)
1.0 (reference)
1.0 (reference)
Schooling (years)
<9 years
5 (8.6)
53 (91.4)
2.43 (0.78–7.55)
2.41 (0.65–8.87)
≥9 years
9 (3.7)
232 (96.3)
1.0 (reference)
1.0 (reference)
Single
Yes
9 (5.5)
156 (94.5)
1.49 (0.49–4.55)
1.19 (0.35–4.03)
No
5 (3.7)
129 (96.3)
1.0 (reference)
1.0 (reference)
Monthly income*
None
2 (8.7)
21 (91.3)
6.38 (0.55–73.94)
6.55 (0.50–86.21)
<1 minimum wage
4 (8.0)
46 (92.0)
5.83 (0.63–53.81)
7.40 (0.66–82.21)
1–5 minimum wages
7 (4.4)
151 (95.6)
3.11 (0.37–25.75)
3.09 (0.35–26.91)
>5 minimum wages
1 (1.5)
67 (98.5)
1.0 (reference)
1.0 (reference)
Alcohol intake
Yes
8 (5.1)
150 (94.9)
1.20 (0.41–3.55)
1.09 (0.34–3.49)
No
6 (4.3)
135 (95.7)
1.0 (reference)
1.0 (reference)
Smoking habit
Yes (ever)
1 (2.9)
34 (97.1)
0.57 (0.07–4.54)
0.44 (0.05–3.70)
No
13 (4.9)
251 (95.1)
1.0 (reference)
1.0 (reference)
BCG vaccination
Yes
12 (5.3)
215 (94.7)
1.95 (0.43–8.94)
2.09 (0.16–28.05)
No
2 (2.8)
70 (97.2)
1.0 (reference)
1.0 (reference)
Doses of BCG†
Two
1 (5.6)
17 (94.4)
0.94 (0.11–7.76)
0.81 (0.09–7.47)
One
11 (5.3)
198 (94.7)
1.0 (reference)
1.0 (reference)
CD4 count
<200 cells/mm³
1 (3.3)
29 (96.7)
0.68 (0.08–5.26)
0.58 (0.07–5.00)
≥200 cells/mm³
13 (4.8)
256 (95.2)
1.0 (reference)
1.0 (reference)
History of contact with index case
Yes
—
35 (100)
0.49 (0.06–3.82)
—
No
13 (5.0)
245 (95.0)
1.0 (reference)
—
No information
1 (16.7)
5 (83.3)
—
—
Legend: LTBI: latent tuberculosis infection; BCG: Bacillus Calmette-Guérin; QTF-GIT: QuantiFERON TB-Gold in-Tube.
*Minimum wage = 615.00 Brazilian reais, equivalent to 349.40 American dollars at the time of data collection. †Percentage calculated over those vaccinated with BCG. One unit added to all cells to allow OR calculation.