Integration Strategy Is a Key Step in Network-Based Analysis and Dramatically Affects Network Topological Properties and Inferring Outcomes

Table 5

Description of the top genes in 11 integration networks from the detection of disease genes based on a phenotype similarity study.

Strategy	Gene symbol	Official full name
Union	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
Intersection	MYD88	Myeloid differentiation primary response 88
2-Vote	TGFBR2	Transforming growth factor, beta receptor II (70/80 kDa)
3-Vote	TGFBR2	Transforming growth factor, beta receptor II (70/80 kDa)
SVM	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
Naive Bayes	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
Random Tree	GRM7	Glutamate receptor, metabotropic 7
J48	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
Logistic Regression	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
Random Forest	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
Bayesian Networks	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2