Research Article

Cecropia pachystachya: A Species with Expressive In Vivo Topical Anti-Inflammatory and In Vitro Antioxidant Effects

Figure 3

Effect of CPM on croton oil multiple application-induced mouse ear edema showing the time-response curve of effect during 9 days. Dark points under times indicate when the croton oil application occurred. The thickness of the ear was measured daily, using a digital micrometer. At the time 120 h (fifth day of the experiment) the ear of the animals received vehicle acetone (negative control), dexamethasone (positive control), or CPM 0.5 mg/ear, twice a day (arrows indicate the days of treatment which treatment). Statistical analysis: two-way ANOVA followed by Bonferroni test ( –8). compared to negative control group.
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