Subunit Composition of Neurotransmitter Receptors in the Immature and in the Epileptic Brain
Figure 2
Effect of the opening of the GABAA receptor associated channel. (a) In the immature neuron, the concentration of Cl− is higher in the intracellular space and, therefore, the opening of the channel leads to an efflux of Cl− and depolarization (excitation). (b) In contrast, in the mature neuron, the concentration of Cl− is higher in the extracellular space and, therefore, the opening of the channel leads to an influx of Cl− and hyperpolarization (inhibition). Legend: Cl−: chloride. IN: intracellular. EX: extracellular.
