Promoting Nerve Regeneration in a Neurotmesis Rat Model Using Poly(DL-lactide--caprolactone) Membranes and Mesenchymal Stem Cells from the Wharton’s Jelly: In Vitro and In Vivo Analysis
Figure 1
Monocultures of HMSCs from Wharton’s jelly over PLC membrane exhibiting a mesenchymal-like shape with a flat polygonal morphology (a). Monocultures of HMSCs from Wharton’s jelly over PLC membrane after 72 h of culture in neurogenic medium; differentiated HMSCs (small white arrows) became exceedingly long and there is a formation of typical neuroglial-like cells with multibranches (b) (magnification: 100x). SEM image of PLC tube-guide with inner diameter highlighted by large white arrow and outer diameter highlighted by small black arrows (magnification: 250x) (c). SEM image of HMSCs (large black arrow highlighting cell) cultured over a PLC disc (magnification: 1000x) (d).
