High Level of Tregs Is a Positive Prognostic Marker in Patients with HPV-Positive Oral and Oropharyngeal Squamous Cell Carcinomas

Table 3

Comparison of the mean values of immunological characteristics between patients with good and bad prognosis (for specification see materials and methods).

Immunological Characteristics	Good Prognosis	Bad Prognosis	𝑃 value	95% CI
	Mean	Mean
CD8+ (%)	26.9	26.0	0.729	−4.4; 6.2
CD4+ (%)	45.8	47.9	0.446	−7.8; 3.5
CD19+ (%)	9.9	13.6	0.222	−9.9; 2.6
CD3−CD56+16+ (%)	11.6	11.0	0.764	−3.5; 4.7
CD4+/CD8+	1.9	2.0	0.632	−7.1; 4.6
CD8+CD4+sum	72.7	73.9	0.779	−6.4; 3.9
Tregs (%)	13.0	10.5	0.417	−3.5; 8.4
CD8+/Tregs	2.8	3.9	0.613	−3.1; 1.9

95% CI: confidence interval; 𝑃: probability.