BioMed Research International / 2014 / Article / Tab 3

Clinical Study

The Role of Vitamin D Deficiency and Vitamin D Receptor Genotypes on the Degree of Collateralization in Patients with Suspected Coronary Artery Disease

Table 3

Vitamin D status and CAD class by VDR genotype.

Characteristics The FOKI VDR genotype, % ( ) value
FFff Ff
54.5 (414)7.6 (58)37.9 (288)

Coronary artery disease
 Class 018.35 (76)13.80 (8)11.80 (34)0.8
 Class 125.10 (104)27.60 (16)28.50 (82)0.8
 Class 219.80 (82)20.70 (12)25.50 (74)0.8
 Class 336.70 (152)37.90 (22)34.00 (98)0.7
Severe vitamin D deficiency 56.76 (235)84.48 (49)85.41 (246)0.01
Well collateralization80.19 (332)51.72 (30)63.88 (184)0.01

Mean ± standard deviation.
Patients were grouped to four classes based on luminal stenosis and the number of coronary arteries involved. In class 0, luminal stenosis was less than 50% and considered normal. In all other classes, whereluminal stenosis was more than 50%, the participants were considered CAD patients: in class 1, luminal stenosis was more than 50% in one artery; in class 2, luminal stenosis was more than 50% in two arteries; in class 3, luminalstenosis was more than 50% in three arteries.
Well collateralization: based on Rentrop scores, patients were categorized into either a poor-collateralization group (grades 0-1) or a well-collateralization group (grades 2-3).
Severe vitamin D deficiency: serum 25(OH)D3 level less than 10 ng/mL was considered as severe vitamin D deficiency.

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