Gene Expression Changes Induced by Trypanosoma cruzi Shed Microvesicles in Mammalian Host Cells: Relevance of tRNA-Derived Halves
Figure 3
Temporal changes of gene expression in HeLa cells induced by extracellular vesicles secreted by T. cruzi. HeLa cells were exposed to 160 ng of EVs fraction for two hours and analyzed at 6, 24, and 72 hours. (a) Table showing the number of differentially expressed genes at different time points. (b) Venn diagrams showing shared and exclusive differentially expressed genes with fold change (FC) ≥ 3. (c) Venn diagrams showing shared and exclusive upregulated genes with FC ≥ 3. (d) Venn diagrams showing shared and exclusive downregulated genes with FC ≥ 3. Experiments were performed by duplicate on three independent samples.
