The Effects of Intravenous Fosaprepitant and Ondansetron for the Prevention of Postoperative Nausea and Vomiting in Neurosurgery Patients: A Prospective, Randomized, Double-Blinded Study

Table 1

Patient demographics.

	NK1 group	ONS group
Patients	𝑛=32	𝑛=32
Age, years	62±10	58±14
Height, cm	158±9	158±6
Weight, kg	59±11	62±9
ASA physical state (𝑛), I/II	2/30	1/31
Risk factor
Tobacco use (𝑛)	2	4
History of motion sickness/PONV (𝑛)	2	2
Women	17	21
Duration of anesthesia, min	460±138	513±166
Duration of surgery, min	366±137	403±197
Intraoperative remifentanil, mg	6.8±4.6	8.0±4.3
Blood loss, mL	291±372	303±287
Fluid volume, mL	3259±1341	3362±1130
Analgesics used postoperatively
Diclofenac sodium (25 mg sup)	5	4
Pentazocine (15 mg i.v.)	1	1
Loxoprofen sodium (60 mg p.o.)	11	12

Dates are expressed as mean ± SD or number of patients.
NK1 group = i.v. fosaprepitant. ONS group = i.v. ondansetron.
PONV = postoperative nausea and vomiting.