The Effects of Intravenous Fosaprepitant and Ondansetron for the Prevention of Postoperative Nausea and Vomiting in Neurosurgery Patients: A Prospective, Randomized, Double-Blinded Study

Table 2

Postoperative values.

	NK1 group,; 𝑛=32	ONS group,; 𝑛=32
0–2 hours
PONV	8 (25%)	12 (38%)
Complete response	23 (72%)	20 (63%)
Vomiting	2 (6%)	8 (25%)
Rescue antiemetic	6	8
VAS pain score	3 (0–5)	4 (0–6)
0–24 hours
PONV	11 (34%)	18 (56%)
Complete response	21 (66%)*	13 (41%)
Vomiting	2 (6%)*	16 (50%)
Rescue antiemetic	8	14
VAS pain score	3 (0–4.75)	3 (0–4)
0–48 hours
PONV	12 (38%)	18 (56%)
Complete response	20 (63%)*	12 (38%)
Vomiting	2 (6%)*	16 (50%)
Rescue antiemetic	10	14
VAS pain score	2 (0–3.75)	2 (0–2.75)

Dates are expressed as number of patients (percentile) or median (interquartile range). NK1 group = i.v. fosaprepitant. ONS group = i.v. ondansetron. PONV = postoperative nausea and vomiting. VAS pain score = visual analog pain score (0 = no pain to 10 = the worst pain imaginable). ^∗𝑃<0.05 compared to ONS group.